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It was discovered that naltrexone and bupropion combined, that could be marketed down the road as Contrave, provide better weight loss results than dieting and exercise alone.

Using two separate drugs to shed pounds can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight-loss and the those who go through it you need to err to the side of caution and allow FDA do its job and demand some research be done so your public understands the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to earn money and that they would say anything to keep people on his or her medications.

Researchers discovered that participants taking this drug for a year, lost excess weight within 4 weeks and have kept the body weight off through the 56 weeks with the study. Contrave is a combination from the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which might be made up of many active ingredient, which may make them more effective and safer.

Combo-pilling may be the newest fad or better yet the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular could be the fact that since right now there are not any long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug can also raise hypertension and heartbeat, and really should not be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high blood pressure levels, along with by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients on the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.

From a psychiatric perspective, evidence points too the ordinary neural mechanism for goal-directed behavior has become hijacked by the addiction, and malfunctions in a way that its ordinary functions are exaggerated and fixated on its object. An object produces a stimulus along with the person engages in a "goal-directed behavioral response" that produces a "natural high"(Bostwick & Bucci, 2008).